Cancer Genome Evolutionary Trajectories in Metastasis

Publication date: 13 January 2020Source: Cancer Cell, Volume 37, Issue 1Author(s): Nicolai J. Birkbak, Nicholas McGranahanMetastatic cancer is a major cause of death and remains largely incurable. A better understanding of metastasis is therefore desperately needed to improve prognosis for late-stage disease. Here we survey the landscape of studies exploring the genomics of metastatic cancer. We consider evidence for genomic drivers of metastasis and explore studies investigating modes of metastatic spread.
Source: Cancer Cell - Category: Cancer & Oncology Source Type: research