LncRNA AFAP1-AS1 promotes osteoblast differentiation of human aortic valve interstitial cells through regulating miR-155/SMAD5 axis AFAP1-AS1 promotes osteoblast differentiation of VICs

ConclusionCollectively, AFAP1-AS1 promotes osteogenic differentiation of VICs, at least in part, by sponging miR-155 to upregulate SMAD5. This study sheds new light on lncRNA-directed therapeutics in DCAVD.
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research