Silencers, Enhancers, and the Multifunctional Regulatory Genome

Publication date: Available online 7 January 2020Source: Trends in GeneticsAuthor(s): Marc S. HalfonNegative regulation of gene expression by transcriptional silencers has been difficult to study due to limited defined examples. A new study by Gisselbrecht et al. has dramatically increased the number of identified silencers and reveals that they are bifunctional regulatory sequences that also act as gene expression-promoting enhancers.

Source: Trends in Genetics - January 8, 2020 Category: Genetics & Stem Cells Source Type: research