Risk of acute kidney injury associated with the use of fluoroquinolones

This interesting study examined the risk of acute kidney injury when using fluoroquinolones. The current use of this class of antibiotics in patients had a >2-fold (95% confidence interval [CI] 1.74-2.73) higher adjusted relative risk (RR) of acute kidney injury compared with no use. Furthermore, the dual use of fluoroquinolones and renin-angiotensin-system blockers had RR of 4.46 (95% CI 2.84-6.99) for acute kidney injury. : Proteinuria: Is the ONTARGET renal substudy actually off target? The effect of combination treatment with aliskiren and blockers of the renin-angiotensin system on hyperkalaemia and acute kidney injury: systematic review and meta-analysis Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Acute Kidney Injury General Nephrology Source Type: research