Population pharmacokinetics of cefuroxime and uptake into hip and spine bone of patients undergoing orthopaedic surgery

ConclusionEven if a majority of patients undergoing hip or spine surgery probably achieved adequate concentrations of cefuroxime, not all patients reached bone concentrations of cefuroxime above a recommended breakpoint for susceptible germs at the time of surgery.

Source: Journal of Pharmacy and Pharmacology - December 19, 2019 Category: Drugs & Pharmacology Authors: Ulrich Gergs, Lina Becker, Richard Okoniewski, Michael Weiss, Karl ‐Stefan Delank, Joachim Neumann Tags: Research Paper Source Type: research