Evaluating side ‐by‐side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

ConclusionThe tested models were comparable; however, Caco ‐2 cell monolayers were considered too sensitive to be used to study drug supersaturation. Further studies are needed to evaluate the observed drug‐dependent effects of absorption on drug supersaturation.

Source: Journal of Pharmacy and Pharmacology - December 25, 2019 Category: Drugs & Pharmacology Authors: Jannik Nicklas Eliasen, Ragna Berthelsen, Anne Louise Slot, Anette M üllertz Tags: Research Paper Source Type: research