Distinct microRNA expression in endometrial lymphocytes, endometrium, and trophoblast during spontaneous porcine fetal loss

Immune cells that reside at the ever-changing maternal–fetal interface interact with fetally derived trophoblast cells in order to develop a tolerance toward the allogeneic fetus (Erlebacher, 2013). During early pregnancy in most mammals, including pigs, the maternal endometrium is enriched by extensive recruitment of immune cells, particularly natural killer (NK) cells, T cells, B cells, macrophages, and dendritic cells (Engelhardt et al., 2002a, Moffett-King, 2002, Peel, 1989, Kammerer et al., 2000).
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research