Foreign body granulomas in oral tissues as a complication of injectable dermal fillers: A case report

Publication date: Available online 27 December 2019Source: Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAuthor(s): Maria Inês Mantuani Pascoaloti, Lilian de Barros, Hayder Egg Gomes, Bruno Sérgio Bahia Lopes, Leandro Junqueira Oliveira, Paulo Eduardo Alencar Souza, Martinho Campolina Rebello HortaAbstractInjectable dermal fillers have been widely used for aesthetic procedures. However, adverse reactions, such as foreign body granulomas, have been reported. Foreign body granulomas are formed in response to foreign bodies that cannot be phagocytosed by macrophages, triggering a granulomatous inflammatory reaction. Here, we report on a case of foreign body granulomas in oral tissues as a complication of injectable dermal fillers and review the pertinent literature. A 55-year-old woman sought dental assistance, complaining of lip asymmetry. During the intraoral examination, two ill-defined nodules were observed bilaterally in the lower labial and buccal mucosa areas, close to the labial commissure. The patient reported history of aesthetic facial filling in the nasolabial sulcus region, bilaterally. An incisional biopsy was performed, and the anatomopathological examination confirmed the diagnosis of foreign body granulomas. Surgical removal of the lesions was not performed. The patient is under clinical follow-up and, after 2 years, shows no signs of changes or complications.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research