Teratology Study of Amide Derivatives of Branched Aliphatic Carboxylic Acids with 4‐Aminobenzensulfonamide in NMRI Mice

CONCLUSIONSIn addition to exerting more potent preclinical antiepileptic activity, teratology comparison indicates that aminobenzensulfonamide analogs are generally more weakly teratogenic than VPA.

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - August 26, 2013 Category: Perinatology & Neonatology Authors: Yuko Onishi, Akinobu Okada, Hiroko Noyori, Ai Okamura, Naama Hen, Boris Yagen, Meir Bialer, Michio Fujiwara Tags: Original Article Source Type: research