Leptin receptor–expressing cells represent a distinct subpopulation of notochord-derived cells and are essential for disc homoeostasis

In conclusion, our data prove LepR-Cre mice useful for mapping the fate of specific subpopulations of IVD cells and uncovering the underlying mechanisms of IDD.

Source: Journal of Orthopaedic Translation - December 24, 2019 Category: Orthopaedics Source Type: research