The Stress Response to Surgery and Postoperative Delirium: Evidence of Hypothalamic-Pituitary-Adrenal Axis Hyperresponsiveness and Decreased Suppression of the GH/IGF-1 Axis

Conclusions: Hypothalamic–pituitary–adrenal axis hyperresponsiveness and a less frequent suppression of the GH/IGF-1 axis in response to acute stress are possibly involved in delirium pathophysiology.

http://jgp.sagepub.com/cgi/content/abstract/26/3/185?rss=1

Source: Journal of Geriatric Psychiatry and Neurology - August 23, 2013 Category: Genetics & Stem Cells Authors: Cerejeira, J., Batista, P., Nogueira, V., Vaz-Serra, A., Mukaetova-Ladinska, E. B. Tags: Articles Source Type: research