Using the structure-function linkage database to characterize functional domains in enzymes.

Using the structure-function linkage database to characterize functional domains in enzymes. Curr Protoc Bioinformatics. 2014;48:2.10.1-2.10.16 Authors: Brown S, Babbitt P Abstract The Structure-Function Linkage Database (SFLD; http://sfld.rbvi.ucsf.edu/) is a Web-accessible database designed to link enzyme sequence, structure, and functional information. This unit describes the protocols by which a user may query the database to predict the function of uncharacterized enzymes and to correct misannotated functional assignments. The information in this unit is especially useful in helping a user discriminate functional capabilities of a sequence that is only distantly related to characterized sequences in publicly available databases. © 2014 by John Wiley & Sons, Inc. PMID: 25501940 [PubMed - in process]
Source: Current Protocols in Bioinformatics - Category: Bioinformatics Tags: Curr Protoc Bioinformatics Source Type: research