Flavonoids from the leaves and twigs of Knema elegans

Publication date: February 2020Source: Biochemical Systematics and Ecology, Volume 88Author(s): Zhao Lu, Wen-Chao Wu, Mei Wang, Jia-Qian Zhang, Ye-Gao Chen, Rui Zhan, Li-Dong ShaoAbstractKnema elegans, a tropical evergreen plant, belongs to Myristicaceae family. Phytochemical investigation on the leaves and twigs of K. elegans led to the isolation and identification of two new flavonoids knemavones A and B (1 and 2), along with fifteen known analogues (3–17). These compounds belong to four subtypes of flavonoids, including chalcones, flavanes, flavones, and isoflavones. The structures of 1 and 2 were elucidated by means of spectroscopic techniques, including HRESIMS, 1D, and 2D NMR experiments. Compounds 3–17 are isolated from the title plant for the first time. Moreover, the new chalcones 1 and 2 could serve as chemotaxonomic markers of K. elegans.Graphical abstract
Source: Biochemical Systematics and Ecology - Category: Biochemistry Source Type: research