Activation of reactive oxygen species ‐mediated mitogen‐activated protein kinases pathway regulates both extrinsic and intrinsic apoptosis induced by arctigenin in Hep G2

ConclusionsOur findings demonstrated that ARG induced apoptosis in HCC via ROS ‐mediated mitogen‐activated protein kinases apoptosis pathway.

Source: Journal of Pharmacy and Pharmacology - December 9, 2019 Category: Drugs & Pharmacology Authors: Zheng Lu, Hongbo Zhou, Shishuo Zhang, Wei Dai, Yan Zhang, Liping Hong, Fanjie Chen, Jiyue Cao Tags: Research Paper Source Type: research