Research and Application Progress of Paper-based Microfluidic Sample Preconcentration

Publication date: December 2019Source: Chinese Journal of Analytical Chemistry, Volume 47, Issue 12Author(s): Si-Jia LIANG, Ji-Kai MAO, Chen GONG, Dong-Dong YU, Jian-Guang ZHOUAbstractSample pretreatment is an important part in detection and analysis of samples, especially for those with low initial concentration. Preconcentration technology can improve the accuracy of analytical method and expand its application range. However, conventional sample preconcentration technology is often cumbersome, costly, time-consuming, and relies on expensive equipment. Paper-based microfluidic sample preconcentration technique has many advantages such as easy preparation, low cost and high efficiency, which can simplify operation and reduce detection cost. This paper focuses on the research and application progress of paper-based microfluidic sample preconcentration in recent years, including enrichment principle, selection of paper-based materials, design of device structure, and the application of this technology. Finally, the development trend of this technique was prospected.Graphical abstractPaper-based microfluidic sample preconcentration technology has the characteristics of easy preparation, easy operation, low cost, high efficiency, and portability. This paper introduces the research progress on paper-based microfluidic sample preconcentration techniques in recent years, including the enrichment principle, selection of paper materials, structure design of paper-based microfluidic s...

Source: Chinese Journal of Analytical Chemistry - December 15, 2019 Category: Chemistry Source Type: research