Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat

In conclusion, this study identifies a role for Syk in acute renal allograft rejection. Syk inhibition may be a useful addition to T‐cell‐based immunotherapy in renal transplantation.

Source: International Journal of Experimental Pathology - October 1, 2014 Category: Pathology Authors: Sharmila Ramessur Chandran, Greg H. Tesch, Yingjie Han, Naomi Woodman, William R. Mulley, John Kanellis, Kate Blease, Frank Y. Ma, David J. Nikolic‐Paterson Tags: Original Article Source Type: research