Effects of Recombinant Adenovirus Hepatocyte Growth Factor Gene on Myocardial Remodeling in Spontaneously Hypertensive Rats

Conclusions:
These findings indicate that HGF expression is attenuated in hypertrophic and fibrotic myocardium of SHR. The forced increase in HGF exerts a salutary effect on myocardial fibrosis, collagen I expression, and hemodynamic parameters.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - August 12, 2013 Category: Cardiology Authors: Hu, Z.-P., Bao, Y., Chen, D.-N., Cheng, Y., Song, B., Liu, M., Li, D., Wang, B.-N. Tags: Experimental Studies Source Type: research