Effects of Direct Renin Inhibition on Atherosclerotic Biomarkers in Patients With Stable Coronary Artery Disease and Type 2 Diabetes Mellitus

Conclusions:
Treatment with either aliskiren or amlodipine did not significantly alter surrogate biomarkers of atherosclerosis in patients with both diabetes and established cardiovascular disease already receiving appropriate secondary cardiovascular prevention therapy. The study is limited in its size and duration to see an effect.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - August 12, 2013 Category: Cardiology Authors: Irons, B. K., Trujillo, A., Seifert, C. F., Simoni, J. S., Doctolero, S., Abo-Salem, E., Meyerrose, G. E. Tags: Clinical Studies Source Type: research