Characterizing stutter variants in forensic STRs with massively parallel sequencing

In conclusion, with massively parallel sequencing technology and our sequence simplification strategy, sequence variations within alleles and stutter products were identified, which was useful to determine the origin of stutters, identify more stutter variants, and explore the relationships among motifs. These findings may be helpful for allele designation, a deeper understanding of the mechanism of stutter, and improving resolution in forensic mixture analyses.
Source: Forensic Science International: Genetics - Category: Forensic Medicine Source Type: research