A case report of catheter-related bloodstream infection due to Trichosporon coremiiforme in a patient with secondary neutropenia to HIV

Publication date: Available online 6 December 2019Source: Journal de Mycologie MédicaleAuthor(s): Victoria Monzani, Susana Córdoba, Matías Vivot, Bárbara Arias, Walter Vivot, Wanda Szusz, Patricia Castellaro, Andrea Appendino, Constanza Giselle TavernaAbstractHere, we describe an invasive infection due to Trichosporon coremiiforme in an HIV positive patient with neutropenia. The strain was first erroneously identified as Trichosporon asahii by conventional methods, but correctly identified by mass spectrometry using matrix-assisted laser desorption/ionization time-of-flight technology (MALDI-TOF MS) and ribosomal DNA sequencing. The infection was successfully resolved after antifungal treatment with amphotericin B and fluconazole. This case report is a contribution to the study of T. coremiiforme infections and reinforces its relevance as a species capable of causing invasive human infection in immunocompromised patients and also contributes to the study of its susceptibility profile against antifungal drugs.

Source: Journal of Medical Mycology - December 7, 2019 Category: Biology Source Type: research