Subtelomeric chromosomal rearrangements in a large cohort of unexplained intellectually disabled individuals in Indonesia: A clinical and molecular study

Conclusion: This is the first study describing the presence of subtelomeric rearrangements in individuals with ID in Indonesia. Furthermore, it shows that also in Indonesia such abnormalities are a prime cause of ID and that in developing countries with limited diagnostic services such as Indonesia, it is important and feasible to uncover the genetic etiology in a significant number of cases with ID.

Source: Indian Journal of Human Genetics - August 5, 2013 Category: Genetics & Stem Cells Authors: Farmaditya E. P. MundhofirWilly M NillesenBregje W. M. Van BonDominique SmeetsRolph PfundtGaby van de Ven-SchobersMartina Ruiterkamp-VersteegTri I WinarniBen C. J. HamelHelger G YntemaSultana M. H. Faradz Source Type: research