A calcium message for Niemann-Pick type C

Calcium is a ubiquitous secondary messenger that is critical for cellular function. In the highlighted article, Tiscione et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201903018) describe a link between lysosomal cholesterol storage, calcium distribution alterations, and neuronal morphology in the neurodegenerative disorder Niemann-Pick type C.

http://jcb.rupress.org/cgi/content/short/218/12/3890?rss=1

Source: Journal of Cell Biology - December 1, 2019 Category: Cytology Authors: Cologna, S. M. Tags: Spotlight Source Type: research