Getting under the skin: Cuticle damage elicits systemic autophagy response in C. elegans

In this issue, Zhang et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201907196) describe a molecular mechanism by which cuticular damage in the nematode C. elegans leads to systemic induction of autophagy by signals propagated from sensory neurons via the TGF-β signaling pathway.

http://jcb.rupress.org/cgi/content/short/218/12/3885?rss=1

Source: Journal of Cell Biology - December 1, 2019 Category: Cytology Authors: Kumsta, C., Hansen, M. Tags: Spotlight Source Type: research