Combined adenocarcinoma with yolk sac tumor of the rectum metastasizing as a germ cell neoplasm: Case report

We reported a case of 18 years-old female patient admitted to Mansoura oncology center with severe abdominal pain. Physical examination revealed a distended abdomen with hepatomegaly with no abdominal mass. Computed tomographic (CT) scan of the abdomen revealed markedly enlarged liver with multiple innumerable variable sized hyper-echoic non-enhanced focal lesions. The patient underwent an ultrasound- guided biopsy of the liver that showed metastatic yolk sac tumor. Colonoscopy confirmed a large polypoidal ulcerating mass that was 15 cm from anal verge. Biopsy from the mass revealed conventional colonic adenocarcinoma merged with yolk sac component. This is the third reported case of a colonic adenocarcinoma with germ cell element of yolk sac tumor. The neoplasm metastasized to the liver as a yolk sac component.
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research