Genetic variants in gluco- and mineralocorticoid receptors are associated with concentrations of plasma cortisol, muscle glycogen content and meat quality traits in male Nellore cattle

The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) are key components in the regulation of the hypothalamic-pituitary-adrenal (HPA) neuroendocrine axis and coordinate the physiological response to stress agents to re-establish homeostasis. Genetic variations of GR (NR3C1) and MR (NR3C2) genes could explain the alterations in animals to adapt to challenges and therefore their influence on production traits. The present study aimed to identify single nucleotide polymorphisms (SNPs) in the bovine NR3C1 and NR3C2 genes and explore their associations to relevant traits of beef cattle production.
Source: Domestic Animal Endocrinology - Category: Endocrinology Authors: Source Type: research