Diaphragm muscle adaptations in health and disease

Publication date: Available online 27 November 2019Source: Drug Discovery Today: Disease ModelsAuthor(s): Matthew J. Fogarty, Gary C. SieckBreathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.
Source: Drug Discovery Today: Disease Models - Category: Drugs & Pharmacology Source Type: research