Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis.
This meta-analysis looks at the effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease. It has been updated from a 2009 meta-analysis (read it here) looking at the same question but with the benefit of additional clinical trial data. Analysis of the trials that reported mortality showed a 22% reduction in all-cause mortality (risk ratio 0·78, 95% CI 0·61-0·98) in patients assigned to non-calcium-based binders.
Will this change your practice? Please comment.
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The demise of calcium-based phosphate binders
Lipid-Lowering Therapy in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis.
Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis
Source: Nephrology Now - Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Bone Mineral Metabolism Chronic Kidney Disease Vascular Disease/Calcification Source Type: research
More News: Calcium | Cholesterol | Chronic Kidney Disease | Clinical Trials | Statin Therapy | Urology & Nephrology