Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis.

This meta-analysis looks at the effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease.  It has been updated from a 2009 meta-analysis (read it here) looking at the same question but with the benefit of additional clinical trial data.  Analysis of the trials that reported mortality showed a 22% reduction in all-cause mortality (risk ratio 0·78, 95% CI 0·61-0·98) in patients assigned to non-calcium-based binders. Will this change your practice?  Please comment. : The demise of calcium-based phosphate binders Lipid-Lowering Therapy in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis. Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Bone Mineral Metabolism Chronic Kidney Disease Vascular Disease/Calcification Source Type: research