Association of IKZF1 SNPs in cold medicine-related Stevens –Johnson syndrome in Thailand

ConclusionIn addition to the Japanese, Korean and Indian populations, Thai cases with CM-SJS/TEN and SOC were significantly associated withIKZF1 SNPs. With our previous report of the critical role ofIKZF1 in mucocutaneous inflammation, these results suggest thatIKZF1 is important in the pathogenesis of CM-SJS/TEN with SOC.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research