Stressing Out about Cancer Immunotherapy

Publication date: 11 November 2019Source: Cancer Cell, Volume 36, Issue 5Author(s): Xue-Yan He, David Ng, Linda Van Aelst, Mikala EgebladStress has long been suspected to negatively influence cancer mortality, yet the molecular mechanisms responsible for this effect have only recently been identified. A new study identifies a stress-induced response in dendritic cells—the activation of the glucocorticoid-inducible transcriptional regulator TSC22D3—as a potent, immunosuppressive effect of stress on cancer.
Source: Cancer Cell - Category: Cancer & Oncology Source Type: research