Seroprotection After Hepatitis A Vaccination in Patients With Drug‐Induced Immunosuppression

ConclusionsLast‐minute vaccination in subjects using immunosuppressive medication is not reliable, only 60% of our subjects had a protective antibody level after a single vaccination. When serology was done within 4 weeks after a single vaccination, seroprotection rates were only 50%, after 4 weeks this number rose to 64%. When persons visit a travel clinic in time for a complete vaccination series, satisfactory seroprotection rates can be reached. Seroprotection rate depends on the drug being used, persons using anti‐TNF alpha are less protected.

Source: Journal of Travel Medicine - July 9, 2013 Category: Infectious Diseases Authors: Wouter van den Bijllaardt, Helen M. Siers, Caroline Timmerman‐Kok, Franciscus G. Pessers, Gerard Natrop, Joep F. van Baars, Nynke Nutma, Douwe van der Werf, Elizabeth H. Gisolf Tags: ORIGINAL ARTICLE Source Type: research