Assessment of biological functions for C3A cells interacting with adverse environments of liver failure plasma

ConclusionsC3A cells cultured with acute liver failure plasma showed mild inhibition of cell viabilities, reduction of albumin secretion, and increase of ammonia accumulation. Furthermore, CYP450 enzymes demonstrated various alterations on gene transcription, protein expression and enzyme activities.
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research