Detailed analysis of dose difference in using water as tissue-equivalent material in 252Cf brachytherapy

ConclusionAssuming water as a tissue-equivalent material, although leads to overestimation of dose rate (except in the case of adipose tissue), is acceptable and suitable for use in 252Cf brachytherapy treatment planning systems based on the recommendation by the ICRU that the uncertainties in dose delivery in radiotherapy should be lower than 5%.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research