New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

In conclusion, our work identified and characterized new actors in the mechanisms of protein transport and secretion and opens stimulating perspectives for the use of our platform in physiological and pathological contexts.

Source: Journal of Cell Biology - November 3, 2019 Category: Cytology Authors: Bassaganyas, L., Popa, S. J., Horlbeck, M., Puri, C., Stewart, S. E., Campelo, F., Ashok, A., Butnaru, C. M., Brouwers, N., Heydari, K., Ripoche, J., Weissman, J., Rubinsztein, D. C., Schekman, R., Malhotra, V., Moreau, K., Villeneuve, J. Tags: Trafficking, Technology Tools Source Type: research