Drive, filter, and stick: A protein sorting conspiracy in photoreceptors

The sorting of proteins into different functional compartments is a fundamental cellular task. In this issue, Maza et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201906024) demonstrate that distinct protein populations are dynamically generated in specialized regions of photoreceptors via an interplay of protein-membrane affinity, impeded diffusion, and driven transport.

Source: Journal of Cell Biology - November 3, 2019 Category: Cytology Authors: Brown, A. I., Koslover, E. F. Tags: Protein Homeostasis, Trafficking, Biophysics Spotlight Source Type: research