Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats.

In conclusion, fenofibrate did not confer any beneficial effect on glucose homeostasis but reduced metformin's glucose-lowering activity in GK rats, thus discouraging the addition of fenofibrate to metformin to improve glycemic control. PMID: 23827952 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23827952?dopt=Abstract

Source: exp Mol Med - July 8, 2013 Category: Molecular Biology Authors: Oh TJ, Shin JY, Kang GH, Park KS, Cho YM Tags: Exp Mol Med Source Type: research