Estimation of serum neopterin level as an early marker for detecting severe dengue infection

ConclusionIn this study, we found that the serum neopterin levels were significantly higher in the severe dengue category (mean: 58.75(±4.91) nmol/l) than in the nonsevere dengue category (mean: 48.11(±8.80) nmol/l). Further, a positive correlation was observed between neopterin concentration and duration of fever; hence, higher serum neopterin levels may indicate dengue severity. Hence, determination of serum neopterin concentration may be used for the early assessment of severe dengue.
Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research