Quantitative Profiling of Platelet-Rich Plasma Indole Markers by Direct-Matrix Derivatization Combined with LC-MS/MS in Patients with Neuroendocrine Tumors [Endocrinology and Metabolism]

CONCLUSIONS:
Direct-matrix derivatization in combination with LC-MS/MS is a powerful tool for the simultaneous quantification of all tryptophan-related indoles in platelet-rich plasma. Simultaneous profiling of relevant indoles improves the biochemical characterization and follow-up of NETs.

Source: Clinical Chemistry - October 28, 2019 Category: Chemistry Authors: van Faassen, M., Bouma, G., de Hosson, L. D., Peters, M. A. M., Kats-Ugurlu, G., de Vries, E. G. E., Walenkamp, A. M. E., Kema, I. P. Tags: Endocrinology and Metabolism Source Type: research