Energy Trade-offs in Host Defense: Immunology Meets Physiology

Publication date: Available online 25 October 2019Source: Trends in Endocrinology & MetabolismAuthor(s): Alexandre A. Steiner, Andrej A. RomanovskyHost defense relies not only on microbicidal mechanisms (resistance), but also on management of collateral damage (tolerance). Here, we discuss how this immunology concept converges with a physiology-born theory on the dichotomy of thermometabolic responses in infection (fever versus hypothermia), yielding a model of immunity that transcends discipline barriers.
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research