Multi-scale agent-based modeling on melanoma and its related angiogenesis analysis
Conclusions:
Simulation results showed that the 3D model can represent key features of melanoma growth, angiogenesis, and its related micro-environment. The model can help cancer researchers understand the melanoma developmental mechanism. Drug synergism analysis suggested that interrupting the communications between melanoma cells and the related vasculatures can significantly increase the drug efficacy against tumor cells.
Source: Theoretical Biology and Medical Modelling - Category: Biomedical Science Authors: Jun WangLe ZhangChenyang JingGang YeHulin WuHongyu MiaoYukun WuXiaobo Zhou Source Type: research
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