An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model
Conclusion:
These results suggest that 18:1 LPA is the predominant ligand responsible for LPA1 and LPA3 receptors-mediated amplification of LPA production through microglial activation.
Source: Molecular Pain - Category: Molecular Biology Authors: Lin MaJun NagaiJerold ChunHiroshi Ueda Source Type: research