Boolean network-based model of the Bcl-2 family mediated MOMP regulation

Conclusions:
In spite of relative simplicity, the Boolean network-based model provides useful insight into main functioning logic of the Bcl-2 switch, consistent with experimental findings.

Source: Theoretical Biology and Medical Modelling - June 14, 2013 Category: Biomedical Science Authors: Tomas TokarZdenko TurcanJozef Ulicny Source Type: research