Genotype Phasing in Populations of Closely Related Individuals

Knowledge of phase has many potential applications for empowering genomic information. For example, phase can facilitate the identification of identical by descent sharing between pairs of individuals, as part of the process of genotype imputation, or to facilitate parent of origin of allele modeling in order to quantify the effect of parental imprinting.

Source: Springer protocols feed by Bioinformatics - January 1, 2013 Category: Bioinformatics Source Type: news