An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis

Conclusions: A quantitative model is presented that attributes the well-known Warburg effect to a biophysical mechanism driven by a convective disturbance in the cell. Contrary to current understanding, this effect may precipitate cancer development, rather than follow from it, providing new insights into carcinogenesis, cancer treatment, and prevention.
Source: Theoretical Biology and Medical Modelling - Category: Biomedical Science Authors: Source Type: research