Distribution of CC-chemokine receptor-5-∆32 allele among the tribal and caste population of Vidarbha region of Maharashtra state

Conclusion: The marginal presence of the allele seen in the studied tribal population could be due to gene flow from the people of European descent. However, lack of the homozygous CCR5-Δ32 mutation and the low prevalence of heterozygous CCR5-Δ32 mutations suggest that the Indians are highly susceptible to HIV/AIDS, and this correlates with the highest number of HIV/AIDS infected individuals in India.

Source: Indian Journal of Human Genetics - June 4, 2013 Category: Genetics & Stem Cells Authors: Arvind B ChavhanSantosh S PawarRajusing G JadhaoKishor G Patil Source Type: research