17PAberrant glycolysis associates with inflammatory tumour microenvironment and promotes metastasis in triple negative breast cancer

ConclusionsUpregulation of IL6/STAT3 signaling axis promotes expression of Glut3 and glycolytic genes. Elevation of Glut3 in TNBC induces macrophage activation and production of pro-inflammatory cytokines. Our data show the possible association between glucose metabolism and inflammatory microenvironment in TNBC.Legal entity responsible for the studyThe author.FundingMinistry of Science and Technology, Taiwan.DisclosureThe author has declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research