20PMatrix metalloproteinases and their tissue inhibitors genes abnormal DNA methylation in breast cancer

ConclusionsTaken that HER2-positive BC is a more aggressive disease, one can assume that unsuppressed expression of the MMP2, MMP23B, MMP24, MMP25, MMP28 genes allowed by the absence of abnormal methylation of their promoters is characteristic for less aggressive BCs. Legal entity responsible for the study: Research Centre for Medical Genetics. Funding: The research was carried out within the state assignment of Ministry of Science and Higher Education of the Russian Federation.Legal entity responsible for the studyResearch Centre for Medical Genetics.FundingMinistry of Science and Higher Education of the Russian Federation.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research