Coxiella burnetii: International pathogen of mystery

Publication date: Available online 28 September 2019Source: Microbes and InfectionAuthor(s): Amanda L. Dragan, Daniel E. VothAbstractCoxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This unique pathogen has been historically challenging to study due to obstacles in genetically manipulating the organism and the inability of small animal models to fully mimic human Q fever. Here, we review the current state of C. burnetii research, highlighting new approaches that allow the mechanistic study of infection in disease relevant settings.
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research