Lung Cancer Screening—Why Do It? Tobacco, the History of Screening, and Future Challenges

The US National Lung Cancer Screening Trial (NLST) begun in 2002 was halted early in October 2010 owing to clear evidence that annual screening with low-dose computed tomography (LDCT) scans led to decreased mortality in the screened population. The NLST posted a 20% reduction in deaths due to lung cancer and a 7% decrease in all-cause mortality.1 Building on decades of research and previous trials, it was the first randomized controlled clinical trial to incontrovertibly validate a mortality benefit from lung cancer screening.

Source: Seminars in Roentgenology - October 17, 2014 Category: Radiology Authors: Patricia M. de Groot, Brett W. Carter, Myrna C.B. Godoy, Reginald F. Munden Source Type: research