Dual therapy of vildagliptin and telmisartan on diabetic nephropathy in experimentally induced type 2 diabetes mellitus rats

Conclusions:
The addition of telmisartan to vildagliptin demonstrated the best control over blood pressure, glycemia and diabetic nephropathy markers, renal structural changes and improvement of renal function as opposed to monotherapy with either drug, possibly because of the dual inhibitory effect on the renin–angiotensin system.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Sharma, A. K., Kanawat, D. S., Mishra, A., Dhakad, P. K., Sharma, P., Srivastava, V., Joshi, S., Joshi, M., Raikwar, S. K., Kurmi, M. K., Srinivasan, B. P. Tags: Original Articles Source Type: research