Protective effects of aliskiren and valsartan in mice with diabetic nephropathy
Conclusion:
Our study indicates that aliskiren and/or valsartan protects against diabetic kidney disease through multiple mechanisms, including decreasing podocyte injury, activation of profibrotic growth factors and proinflammatory cytokines, ER stress and accumulation of lipids.
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - Category: Biomedical Science Authors: Wang, W., Qiu, L., Howard, A., Solis, N., Li, C., Wang, X., Kopp, J. B., Levi, M. Tags: Original Articles Source Type: research
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