Protective effects of aliskiren and valsartan in mice with diabetic nephropathy

Conclusion: Our study indicates that aliskiren and/or valsartan protects against diabetic kidney disease through multiple mechanisms, including decreasing podocyte injury, activation of profibrotic growth factors and proinflammatory cytokines, ER stress and accumulation of lipids.
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - Category: Biomedical Science Authors: Tags: Original Articles Source Type: research